WuXi Biologics
Offering End-to-End Solutions
质谱表征
质谱表征卓越中心（Mass Spectrometry Center of Excellent）为复杂的工艺研发和产品生产、调查等提供质谱技术支持，如蛋白质质谱结构表征分析，蛋白质精细表征分析，蛋白质糖谱表征分析，宿主蛋白质质谱分析。中心拥有8台一流的质谱设备，30+质谱分析专家，已完成100+各类型分子的质谱表征，包括mAb, Bi-specific, Fusion protein等。
中心为客户提供完整的质谱表征策略，
并积极承接独立的质谱分析业务：
- Sequence coverage by LC-MS/MS
- N- and C-terminal sequence by LC-MS/MS
- Post-translational Modification by LC-MS/MS
- Disulfide linkage analysis by LC-MS
- Intact/deglycosylated intact mass analysis by LC-MS
- Reduced/deglycosylated reduced mass analysis by LC-MS
- Middle level Ides digestion mass analysis by LC-MS
- CE-MS with 908 Device
- Quick N-Glycan analysis by LC-MS
- N-glycosylation ID and analysis by FLD and HILIC-MS
- N and O-glycosylation ID and analysis by glycopeptides using LC-MS/MS
- N- or O-glycosylation sites by LC-MS/MS
- Qualitative ID HCP proteins by LC-MS/MS
- Quantitative measurement of HCP proteins by LC-MS/MS
- Sequence variants analysis by LC-MS/MS
- Impurity characterization (peak fractionation and characterization)
- MSn technique to identify mutation and rare PTMs
主要设备
